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    Science FridayAn Off-The-Grid Nobel Win, And Antibiotics In Ancient Microbes
    18 minEpisode 1142

    An Off-The-Grid Nobel Win, And Antibiotics In Ancient Microbes

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    This year’s Nobel Prize in Physiology or Medicine went to three people whose combined discoveries outlined the role of the peripheral immune system—how the immune system knows to attack just foreign invaders and not its own tissues and organs. But when the phone rang for Shimone Sakaguchi, Mary E. Brunkow, and Fred Ramsdell, only two of them picked up.

    Host Ira Flatow talks with Nobel Prize winner Fred Ramsdell, co-founder and scientific advisor at Sonoma Biotherapeutics.

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    © Science Friday and WNYC StudiosLength 18 min11 October 2025Episode 1142ScienceFactsEducationalUSAEpisodic

    Agricultural Bees, China’s Energy Future, Frankenstein In Class. Feb 2, 2018, Part 1

    Agricultural Bees, China’s Energy Future, Frankenstein In Class. Feb 2, 2018, Part 1

    This is an episodic podcast, so you can listen to it in any order, but episode one is a great place to start.

    Listen to episode one here
    11+ScienceFactsEducationalUSAEpisodic11 October 2025© Science Friday and WNYC Studios

    This year’s Nobel Prize in Physiology or Medicine went to three people whose combined discoveries outlined the role of the peripheral immune system—how the immune system knows to attack just foreign invaders and not its own tissues and organs. But when the phone rang for Shimone Sakaguchi, Mary E. Brunkow, and Fred Ramsdell, only two of them picked up.

    Host Ira Flatow talks with Nobel Prize winner Fred Ramsdell, co-founder and scientific advisor at Sonoma Biotherapeutics.

    Plus, Ira talks with bioengineering professor César de la Fuente, who looks for solutions to the antibiotic resistance crisis in unexpected places. Now, he’s used AI to help identify promising antibiotic candidates lurking in ancient archaea, small organisms that can survive some of the most extreme conditions in the world.

    Guests:

    Dr. Fred Ramsdell is the co-founder and scientific advisor at Sonoma Biotherapeutics.

    Dr. César de la Fuente is an associate professor of bioengineering at the University of Pennsylvania.

    Transcripts for each episode are available within 1-3 days at sciencefriday.com.

    Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374

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    © Science Friday and WNYC Studios |Original Episode URL. The content, artwork and advertising within this podcast is not owned or affiliated with Sound Carrot and remain the property of their respective owners.


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