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    Science FridayBiologists Call For A Halt To ‘Mirror Life’ Research
    18 minEpisode 940

    Biologists Call For A Halt To ‘Mirror Life’ Research

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    You’re probably familiar with the concept of handedness—a glove made for your left hand looks basically like the one for your right hand, but won’t fit—it’s a mirror image. Many of life’s important molecules, including proteins and DNA, are chiral, meaning they can exist in either a left-handed or a right-handed form. But on Earth, nature only uses one version or the other in living organisms. Your proteins, for example, are all the left-handed version, while your DNA is all right-handed.

    With advances in synthetic biology, it could be possible to build an artificial organism that flips that shape, having right-handed proteins and left-handed DNA. Writing in the journal Science, an international group of researchers recently cautioned against anyone trying to create that sort of so-called mirror life, saying that it poses the threat of “unprecedented and irreversible harm” to human health and global ecosystems.

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    © Science Friday and WNYC StudiosLength 18 min8 January 2025Episode 940ScienceFactsEducationalUSAEpisodic

    Agricultural Bees, China’s Energy Future, Frankenstein In Class. Feb 2, 2018, Part 1

    Agricultural Bees, China’s Energy Future, Frankenstein In Class. Feb 2, 2018, Part 1

    This is an episodic podcast, so you can listen to it in any order, but episode one is a great place to start.

    Listen to episode one here
    11+ScienceFactsEducationalUSAEpisodic8 January 2025© Science Friday and WNYC Studios

    You’re probably familiar with the concept of handedness—a glove made for your left hand looks basically like the one for your right hand, but won’t fit—it’s a mirror image. Many of life’s important molecules, including proteins and DNA, are chiral, meaning they can exist in either a left-handed or a right-handed form. But on Earth, nature only uses one version or the other in living organisms. Your proteins, for example, are all the left-handed version, while your DNA is all right-handed.

    With advances in synthetic biology, it could be possible to build an artificial organism that flips that shape, having right-handed proteins and left-handed DNA. Writing in the journal Science, an international group of researchers recently cautioned against anyone trying to create that sort of so-called mirror life, saying that it poses the threat of “unprecedented and irreversible harm” to human health and global ecosystems.

    Dr. Drew Endy, a synthetic biology researcher at Stanford University and one of the authors of that warning, joins Ira to discuss the concept of mirror life and why a group of researchers felt compelled to call for a halt to mirror life experiments.

    Transcripts for each segment will be available after the show airs on sciencefriday.com.

    Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374

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    © Science Friday and WNYC Studios |Original Episode URL. The content, artwork and advertising within this podcast is not owned or affiliated with Sound Carrot and remain the property of their respective owners.


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