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You’re probably familiar with the concept of handedness—a glove made for your left hand looks basically like the one for your right hand, but won’t fit—it’s a mirror image. Many of life’s important molecules, including proteins and DNA, are chiral, meaning they can exist in either a left-handed or a right-handed form. But on Earth, nature only uses one version or the other in living organisms. Your proteins, for example, are all the left-handed version, while your DNA is all right-handed.
With advances in synthetic biology, it could be possible to build an artificial organism that flips that shape, having right-handed proteins and left-handed DNA. Writing in the journal Science, an international group of researchers recently cautioned against anyone trying to create that sort of so-called mirror life, saying that it poses the threat of “unprecedented and irreversible harm” to human health and global ecosystems.
You’re probably familiar with the concept of handedness—a glove made for your left hand looks basically like the one for your right hand, but won’t fit—it’s a mirror image. Many of life’s important molecules, including proteins and DNA, are chiral, meaning they can exist in either a left-handed or a right-handed form. But on Earth, nature only uses one version or the other in living organisms. Your proteins, for example, are all the left-handed version, while your DNA is all right-handed.
With advances in synthetic biology, it could be possible to build an artificial organism that flips that shape, having right-handed proteins and left-handed DNA. Writing in the journal Science, an international group of researchers recently cautioned against anyone trying to create that sort of so-called mirror life, saying that it poses the threat of “unprecedented and irreversible harm” to human health and global ecosystems.
Dr. Drew Endy, a synthetic biology researcher at Stanford University and one of the authors of that warning, joins Ira to discuss the concept of mirror life and why a group of researchers felt compelled to call for a halt to mirror life experiments.
Transcripts for each segment will be available after the show airs on sciencefriday.com.
Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
QUICK LINKS
This is an episodic podcast, so you can listen to it in any order, but episode one is a great place to start.
Listen to episode one hereYou’re probably familiar with the concept of handedness—a glove made for your left hand looks basically like the one for your right hand, but won’t fit—it’s a mirror image. Many of life’s important molecules, including proteins and DNA, are chiral, meaning they can exist in either a left-handed or a right-handed form. But on Earth, nature only uses one version or the other in living organisms. Your proteins, for example, are all the left-handed version, while your DNA is all right-handed.
With advances in synthetic biology, it could be possible to build an artificial organism that flips that shape, having right-handed proteins and left-handed DNA. Writing in the journal Science, an international group of researchers recently cautioned against anyone trying to create that sort of so-called mirror life, saying that it poses the threat of “unprecedented and irreversible harm” to human health and global ecosystems.
Dr. Drew Endy, a synthetic biology researcher at Stanford University and one of the authors of that warning, joins Ira to discuss the concept of mirror life and why a group of researchers felt compelled to call for a halt to mirror life experiments.
Transcripts for each segment will be available after the show airs on sciencefriday.com.
Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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